Mechanismen der Immunabwehr

Hautklinik

Direktor:
Prof. Dr. med. univ. Gerold Schuler

    The main focus of the RNA-group is RNA-transfection of dendritic cells (DC), for the purpose of HLA class I presentation of the transfected antigens (Ag). The cytoplasmic expression within the DC allows the Ag to be processed like endogenous proteins, leading to classical HLA class I presentation. The final goal is on the one hand a functional therapeutic vaccine against melanoma and other types of cancer, and on the other hand, to better understand the processes involved in presentation of cellular Ags and the conditions of efficient T-cell priming. But also the manipulation of DC-function, for example by expression of surface receptors, is a strategy embarked by us.

    Arbeitsgruppenleiter


    Post-Docs

    Dr. med. Ugur Uslu
    Telefon: 09131 85-35000
    E-Mail: ugur.uslu@uk-erlangen.de
    Visitenkarte

    PhD Studentin


    MTA/BTA

    Valentina Eberlein, BSc.


    Bachelor- and Master-Studenten

    ...sind immer willkommen!

    Bianca Simon, BSc.

    Lena-Marie Martin, BSc.


    Ehemalige Mitarbeiter

    Alexander Paulus
    Bianca Sänger, derzeit: BioNTech RNA Pharmaceuticals GmbH, Mainz, Germany
    Birgit Schulz
    Christian Krug
    Christian Hofmann, derzeit: UCLA, Med. Infectious Diseases, Los Angeles, California, USA
    Christian Wohn, derzeit: Centre d'Immunologie Marseille-Luminy, Marseille, France
    Ina Müller, derzeit: Universitätsklinikum Erlangen. Dept. Of Cardiac Surgery, Erlangen, Germany
    Isabell Pfeiffer
    Katrin Birkholz, derzeit: MagForce AG, Martinsried, Germany
    Lorenz Kulzer, derzeit: Universitätsklinikum Erlangen, Erlangen, Germany
    Maike Effern, derzeit: Universitätsklinikum Bonn, Institute for Clinical Chemistry and Clinical Pharmacology
    Peter Thumann
    Sabrina Prommersberger
    Sandra Höfflin
    Tanja Moritz
    Valentina Eberlein
    Verena Kubesch


     
     
     
     
     
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